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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d1bf5e58a657ae33964d007007013126e851513e1344689cb26f125269723d3' 
  AND token = 'VMWBoKRK42nkoQTSz7MeMddUtdur8IqOib5Ys7mfvlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}