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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'add78a36e533db10a47b788062ab8866c106f495f9b4f2720a22edeb249b17e5' 
  AND token = 'XhUdDnPgPzFaAxY3657Wf486iHdc7UAwdwr6OgLAemk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}