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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7b6ccf2650a7d17f800cd7f7f937d70be8f1f57f8881336c11a571ec3123264' 
  AND token = 'JdjLf7NUz5rYqvNdRbvWH0VUXyHr2V9mvn91+W3rU5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}