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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eafc2ab8e2c7fdbb46bc58d16569220296fe4315872470715e089d640198b5fa' 
  AND token = '1WORg/JloT+fRThORj47VONn+9RgJjMoqbfdNpf8K7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}