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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2950b106d65099cd1b8d5e4c13be4b5726dbb88cb00f98999d08102e8c270d92' 
  AND token = 'cDorbiYm6sWWgGRVs77CqxRcyIzoXrgQcRUZ6VeEJ4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}