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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48c4d4b857555a97d67e571390ca9d1841ba12cf2eb6a29d6717d9b6fe7501b' 
  AND token = 'IrSJezQEQCTY0KKR/h3h70U0uSVsbxT5RdXjv+pLkfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}