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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817067680c07d420770ae08ae2dff7b654dc5270ca3e520574cb60ab74be7709' 
  AND token = 'gn8rNLUcQTIWL7wcR6cW2fa/tFuk/FmwNUxYJSpc1Bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}