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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344b04d67d166a3925f625ae77dc6e722b2ce9e2624c12cf9e2f6d7e11002c10' 
  AND token = 'O4DkKEVwL+6uGUDun6lCLUAK6Igbsv+bDAdU1uCMve0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}