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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8d2acf059ed70f6ce8d77b4dedec15cc15c6d374bcef481fa7e306447ac786' 
  AND token = '8+SDzQFUjYFRkM7/j1n9JAgy9xjO8dOr7PF6qmx3zyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}