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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de80d5d314a20372d843428c8255af036fe187935d37f98d4a1731457a913c6' 
  AND token = '2uKQJVdKugosZK2ClBMKmdaVhyN0Mdo/hVAC5qDZvCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}