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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5059265b053b45dea43960e6a818410d80f708242b4f2f44116da651cdf5e464' 
  AND token = '8U5I1E8MFgZKLh5OOEmSVDPGaT/6lpj28gYTR6NQbDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}