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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e1eb4e9ed7e4a6196e0b4802f9a348d1cfb7a0e3e26efd26a0ab784364e3f5' 
  AND token = 'K4J356fzInRASKfw6DOz8jFsSffvRv0k31UpyGOfQuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}