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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6babde0c351510608c5e2a620835d29742cd0d6c6b6ee65e38133b378aa29ad' 
  AND token = 'z79HVF3e9mnoSo6s6RDeQUfG4OoagmZnj3iXFYcaJzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}