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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5572f543670684e567460428a9aac7bff003dfdc360598d809f9e6899d5b28' 
  AND token = 'dW2WAmbp2vWae/ARIK5uj9FWkJ+sUp4f1hLPEdfc2oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}