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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6454875cc21f9875d3a4fb6a878bb3ca6b9d06a01f9c1363e0599a9b285fa753' 
  AND token = '8WRVxCzwkXvipxyMqT8uEsebH920i6xYVFqXmox6b+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}