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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5f963ea8b7c09c0ebeda52617a680f1fde6e0e2550c2dfe244e94a767b07f6' 
  AND token = '0ALQ8iYzOURGsOquR78t/zWP7jlJJaEkDn93TdAfiXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}