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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f02fe46fc42438385150e18e7edc413c7803b59b56f2bb2bdc602a0e281cbad' 
  AND token = 'xTh8Unm4nzp0G4W03bMVczgK8b0viuMe5MUwTC/jcTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}