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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '015ce5c643f77ea4826d82a169015bc08942a036cc51a6db02bcd255dd106dbd' 
  AND token = 'D+LPS8e/fKXdOqDYmb0JlwRlS875CqQA16FUQ92Oij4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}