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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7745e42bab40fe7c34a2bc56adaf5997b4a6038539042fd96d6a8e7cf4685121' 
  AND token = 'gIXGMfL8T4nZKQbd5bxG25PK3O9qveEf1ltmV6GQbtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}