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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0e7b7f567661e91ce08a1671dd1f7602b33ae3e1326914ca81532b9fcebc6d' 
  AND token = 'Gw+tBo79nGCVost0kbimxRTn9fuOXdJV+PL7W8a6yYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}