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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2478af20478a1e5833513c9d7cdaf40d1c410ce41046f003af8b449098ff6abb' 
  AND token = 'Ps5f4mIUITEXQeMT3qB0T7wUgQBQQWFo4Md+Lfz/YCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}