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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d5c991e3ac6758213bcdbbd243b303dc5c52c4c6f2643c58730373f7e4dfe8f' 
  AND token = 'VujJI2aPGoQQjTFbfkZhTMwL6jpW+tFa1jiNsNOfvQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}