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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6105611b3431003c2ae0545e2358f0ba28c9661e1ec089f223f7331b0ee916' 
  AND token = '9rdeZHANE99UJHwcZXKWHRdhTRMD0zmLIS9EQFfganI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}