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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7f378eb04b902e297cd27d40ee8c0679bb32c4ddc2873b4de8a6f81261d661b' 
  AND token = 'F4a2JkdfZxJfCywgS6gFWsjqiVhmXCbl67xAwW8p2AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}