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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd33cb9f528afb2b6b2bd4190c13c530cc729a9c6b36294acbf1436bd3e250e5' 
  AND token = 'Ey0Dcpxd6plriWvyuW9Bj22xV7tUVQtcg3Nsb1m9CMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}