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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e680886d8529a0d5fbd0287bea25edb2aa0477df8d3b4859abf5de764e2cd82' 
  AND token = '58UmM+QAJPElUO+7MuyEPTzDw+85gS9kywTqSg5KTC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}