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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0907574c32289606d329b524e3c9019df5a8157027ebe901bf1679d711e7bc2' 
  AND token = 'ILyeHnDFFFBOMxHpIHwtp578qJufAbvLLIvLd/6klWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}