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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3393ba34652a2c212a87b5c49346602b69b9cc25567fcb6ce4e26854f2caeca' 
  AND token = 'A4fTNB0G2vTErKZRuEnTS8u51D7It13hjeD2cgR5r8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}