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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b300b234b7b1908035862a3b078e87e18bd647c846cc1fe3b101d3ea9e11209d' 
  AND token = 'J71KOT7VczqZVy0eyD8kHUhOxaIs9CbSj9sSCKtAeAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}