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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71fa1a6b9ed969ef31beb7f49aa209375e00af8e31905e2eee6a09e7a10d7ddb' 
  AND token = 'tIcozTB9JbDT+s88UXMsczDh4S4cdfylL4H0JtVXg9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}