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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522c145bd1f6e1bd92f0f3878ecffef6e867d550128e3ccc39915f28a5de9fa8' 
  AND token = 'ax9GM9Yh73NpDvMq2+BPF3k5avR9ePh0CtZwM4IgX+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}