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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69c356ef0343a4e37892ee64e4f3109bea0657db367b1229e39cf1ffbd211f3d' 
  AND token = 'G/SY0LWo9rCemyTMd4KuXOzWSSJcgqFF8vRXBV9Qk9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}