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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c17ee3c8b0cb2205bc9c87c16afe3971030a3d8d2401edd6155c221794fcc20' 
  AND token = 't3ATBSoMRYZ5SMpeQUf9mndX4uXbj3NqA6LsCYhoSzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}