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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73c2b4e2aef9fe9947d8f46de39b8a755778d0a13be3f3d15004e035b76307b8' 
  AND token = 'R+t0A9jC3rflFAFkeC5ABEqeDUTamR0iyTP4ZJTgqKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}