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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9ddd6b4ee309a0ea74316bd826b4c78ec05cbe7a9103deb326b016bb9e51a2' 
  AND token = 'CE6+XlSkkfS03frhIS9Oh4rLtY8fyLWtJVRGT4PitwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}