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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '556a221622f3b25bca6fac32671bd1f631d115b9a29bb9fe120c38f437f4debe' 
  AND token = 'nXKxp6nWbBQJH+Rh1k5Y1RK3iRtZKiBUQUKu1+W0k7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}