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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45030bf5537ec44162ea416de82f8e19c340b7f704009f1084d61c24ab7b26b9' 
  AND token = 'KWxNRZk2viaPwZwWRwSSpY/PRs+oyGIykJv+74qR9cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}