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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346d73ad1c8910c4900b8d2fb2a7440b9ebbb1795c9b3372f496ea00c67b88da' 
  AND token = 'uLJPRXnZF0ltPZLrsm5+7PkthkItfly6iP7OrfnrWbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}