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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb8d56fbbfafc92768ee46770c39b5ebbe885e71e69dbe450507ac4b52adad7f' 
  AND token = 'ycPR0BPZ+aWeEMEwxXwvP2piCcV0/xB2KDXEiRe5kn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}