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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36814e1f029539109bd5ae6db6bcca72ce1a427c4f18b4eb705359f05eda0a16' 
  AND token = 'eea/2uC7h1zhdg8INYSAMykXGTvHtoVDBFym8rqfkaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}