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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dde5a01434d0a6ea127398d18b528ba0139e355d234a33c6bb8bfd5e5f004895' 
  AND token = 'IRW0rJpuNoOb5vDSu+lFMKZWH4gBcsrZ6pV+FeJTWtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}