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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d8cac23ffc1a2a2fe8079b51b3fcde26ce0c800c309e4b7c0a1357be353e01' 
  AND token = 'mUYIOeHZDwnX+WC9yjS4QG4+AzgEnFaP0e2AJ/xxbEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}