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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f874f75b8016151f83b86c65ab270c759d707b74020184f740117ebec5cd98' 
  AND token = '2SoXoVd3uJ8G0KFGtCyi/yavkcAeQMJ7I+XwJVbaAAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}