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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ebfe67fdfca68c6c6f00d7be872286d52db28debd64d3256c284af2292f2ff' 
  AND token = 'zXQXGKsE4g+Ue4920xuXzmbM0vfhP24KXmZQkKzpXJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}