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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '801694f381ab40da8c5b1a6aa9751aa3982c3035dabcbe2b1a7d28410567c925' 
  AND token = 'z1YDlTpsI+oo2LC+LFBexm+RDGRJr+NcsBQMHUP/23Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}