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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3685ff6f040b5774959bcae12438a7f126cd421357109efd734f76b033ab8f4d' 
  AND token = 'zQ3qvtQwlh63yqxFCG0LBDHmFfR6hwi9vc427SvssIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}