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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3555a1a7ba110f4a78a98629ba7cab2b5f0214486f49dfb721e8d3f67b971072' 
  AND token = '9ijxlBsG6oHnlXxalRF+Gfly5DaMqs7otURv6d4HrcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}