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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d681be58126e9597e3b81e45983767479af32d27b01c2c08cc50b151365ebc' 
  AND token = '2xs8I7TWsIU8WTGOL7CKvADRx7PuGYsPiG4qfFg0/V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}