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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1a181d9bba8e4044f60dffc0969fc6229f631c0109b0cc8a58933ff63bbde18' 
  AND token = 'ZYdzWn8SB6SiBGxaG1D1PoJtfHtWw6gJwfov0qvHA7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}