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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46429783e2b7a0f386239bc65744c27fc7c35f998802accd86c0529c9ee505b8' 
  AND token = 'CDtK6+/hRYppwu3OhMbYtNApAaoPQqyNuk8qg8gJA/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}